Molecular Formula | C13H15BrClN |
Molar Mass | 300.62 |
Physical and Chemical Properties | Chemical properties 1-bromo -2-cyanide -2-(4-chlorophenyl) hexane pure product is colorless transparent viscous liquid, industrial products are brown viscous liquid, and gradually solidified after long-term storage, B. p.205 ~ 207 ℃/1.333kpa, insoluble in water, soluble in toluene, xylene, acetone and other organic solvents. |
Use | Use 1-bromo-2-cyano-2-(4-chlorophenyl) hexane is an intermediate of bactericide mycloxazole and myxazole. |
its preparation method is to add 2-(4-chlorophenyl) hexonitrile, dibromomethane, solvent dimethyl sulfoxide and catalyst into the reaction kettle, add NaOH aqueous solution dropwise at stirring and room temperature at a temperature of not more than 40 ℃, stir at the temperature for 0.5h after adding, then heat up to 50 ℃ for 8h, and then move the reaction solution to the neutralization kettle after the reaction is over, cool to 0 ℃, add hydrochloric acid dropwise to neutralize to neutral, then add toluene for extraction, the extract is washed with water, and the toluene solution after washing is dissolved to obtain the product.